2023-04-01T09:55:16Zhttp://oaipmh.hindawi.com/oai-pmh/oai.aspx
oai:hindawi.com:10.1100/2012/108953 2012-12-25T09:54:22Z HINDAWI.TSWJ:2012
10.1100/2012/108953DOI Gulec Balbay, EgeDepartment of Chest Diseases, Faculty of Medicine, Duzce University, 81620 Duzce, Turkey Serum IgE Antibodies against Hazelnut in Hazelnut Processing Workers The Scientific World Journal2012-12-25 5 Aim. Previous studies have shown a higher sensitization rate to hazelnut in processing workers but no relation was found between the respiratory symptoms in workplace and hazelnut sensitization. Material and Method. To evaluate the association between the hazelnut sensitization and workplace-related respiratory complaints, hazelnut processing workers had undergone a questionnaire included work-related respiratory symptoms, smoking history, pulmonary function testing, and measurement of serum IgE antibodies against hazelnut. Results. This study consisted of 88 hazelnut processing workers (79 females and 9 males), aged 14–59 years (Mean ± SD: years). The mean working duration was months (min: 1–max: 180). Specific IgE against hazelnut allergens was positive in 14 of cases (17.1%). There was no significant difference between the cases with and without specific IgE against hazelnut allergens regarding respiratory symptoms, history of allergy, smoking status and spirometric values. Conclusion. 17.1% of the hazelnut processing workers were seropositive against hazelnut. Being sensitized to hazelnut was not found to be associated with work-related respiratory symptoms in this study. Further studies are needed in hazelnut workers respiratory health to search topics other than asthma. CC-BY-3.0http://creativecommons.org/licenses/by/3.0/ Copyright © 2012 Ege Gulec Balbay et al. Karatas, NaciyeDepartment of Chest Diseases, Faculty of Medicine, Duzce University, 81620 Duzce, Turkey Arbak, PeriDepartment of Chest Diseases, Faculty of Medicine, Duzce University, 81620 Duzce, Turkey Binay, SongulDepartment of Chest Diseases, Faculty of Medicine, Duzce University, 81620 Duzce, Turkey Yavuz, OzlemDepartment of Biochemistry, Faculty of Medicine, Balikesir University, 10145 Balikesir, Turkey Annakkaya, Ali NihatDepartment of Chest Diseases, Faculty of Medicine, Duzce University, 81620 Duzce, Turkey Balbay, OnerDepartment of Chest Diseases, Faculty of Medicine, Duzce University, 81620 Duzce, Turkey Toru, UmranDepartment of Chest Diseases, Faculty of Medicine, Duzce University, 81620 Duzce, TurkeyORCID-0000-0001-9988-8983 The Scientific World Journal20121089532012 SCOAP3Hindawi https://doi.org/10.1100/2012/108953Full text URL
oai:hindawi.com:10.1155/2014/543195 2014-04-24T08:04:45Z HINDAWI.TSWJ:2014
10.1155/2014/543195DOI Sharma, SujataDepartment of Biophysics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India Singh, Tej P.Department of Biophysics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India Current Overview of Allergens of Plant Pathogenesis Related Protein Families Hindawi Publishing Corporation2014-02-16 19 Pathogenesis related (PR) proteins are one of the major sources of plant derived allergens. These proteins are induced by the plants as a defense response system in stress conditions like microbial and insect infections, wounding, exposure to harsh chemicals, and atmospheric conditions. However, some plant tissues that are more exposed to environmental conditions like UV irradiation and insect or fungal attacks express these proteins constitutively. These proteins are mostly resistant to proteases and most of them show considerable stability at low pH. Many of these plant pathogenesis related proteins are found to act as food allergens, latex allergens, and pollen allergens. Proteins having similar amino acid sequences among the members of PR proteins may be responsible for cross-reactivity among allergens from diverse plants. This review analyzes the different pathogenesis related protein families that have been reported as allergens. Proteins of these families have been characterized in regard to their biological functions, amino acid sequence, and cross-reactivity. The three-dimensional structures of some of these allergens have also been evaluated to elucidate the antigenic determinants of these molecules and to explain the cross-reactivity among the various allergens. CC-BY-3.0http://creativecommons.org/licenses/by/3.0/ Copyright © 2014 Mau Sinha et al. Sinha, MauDepartment of Biophysics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India Singh, Rashmi PrabhaDepartment of Biophysics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India Kushwaha, Gajraj SinghDepartment of Biophysics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India Iqbal, NaseerDepartment of Biophysics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India Singh, AvinashDepartment of Biophysics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India Kaushik, SanketDepartment of Biophysics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India Kaur, PunitDepartment of Biophysics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, IndiaORCID-0000-0002-7358-3716 The Scientific World Journal20145431952014 SCOAP3Hindawi https://doi.org/10.1155/2014/543195Full text URL
oai:hindawi.com:10.1155/2013/208705 2014-05-06T12:17:01Z HINDAWI.TSWJ:2013
10.1155/2013/208705DOI Xavier-Elsas, PedroDepartment of Immunology, Instituto de Microbiologia Professor Paulo de Góes, Universidade Federal do Rio de Janeiro, CCS, Bloco I, Room I-2-066, 22205-020, Rio de Janeiro, Brazil Essential Roles of PKA, iNOS, CD95/CD95L, and Terminal Caspases in Suppression of Eosinopoiesis by PGE2 and Other cAMP-Elevating Agents Hindawi Publishing Corporation2013-11-24 13 Up- and downregulation of eosinopoiesis control pulmonary eosinophilia in human asthma. In mice, eosinopoiesis is suppressed in vitro by prostaglandin E2 (PGE2) and in vivo by diethylcarbamazine, through a proapoptotic mechanism sequentially requiring inducible NO synthase (iNOS) and the ligand for death receptor CD95 (CD95L). We examined the roles of iNOS, cAMP-mediated signaling, caspases, and CD95L/CD95 in suppression of eosinopoiesis by PGE2 and other agents signaling through cAMP. Bone-marrow collected from BALB/c mice, or from iNOS-, CD95-, or CD95L-deficient mutants (and wild-type controls), was cultured with interleukin-5 (IL-5), alone or associated with PGE2, cAMP-inducing/mimetic agents, caspase inhibitor zVAD-fmk, iNOS inhibitor aminoguanidine, or combinations thereof, and eosinopoiesis was evaluated at various times. PGE2, added up to 24 hours of culture, dose-dependently suppressed eosinopoiesis, by inducing apoptosis. This effect was (a) paralleled by induction of iNOS in eosinophils; (b) duplicated by sodium nitroprusside, isoproterenol, and cAMP-inducing/mimetic agents; (c) prevented by protein kinase A inhibition. NO was produced through iNOS by dibutyryl-cAMP-stimulated bone-marrow. Overall, PGE2 and isoproterenol shared a requirement for four effector elements (iNOS, CD95L, CD95, and terminal caspases), which together define a pathway targeted by several soluble up- and downmodulators of eosinopoiesis, including drugs, mediators of inflammation, and cytokines. CC-BY-3.0http://creativecommons.org/licenses/by/3.0/ Copyright © 2013 Bianca de Luca et al. de Luca, BiancaDepartment of Pediatrics, Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, FIOCRUZ, Avenue Rui Barbosa 716, 22250-020 Rio de Janeiro, RJ, Brazil Barradas, MônicaDepartment of Immunology, Instituto de Microbiologia Professor Paulo de Góes, Universidade Federal do Rio de Janeiro, CCS, Bloco I, Room I-2-066, 22205-020, Rio de Janeiro, Brazil Luz, Ricardo A.Department of Immunology, Instituto de Microbiologia Professor Paulo de Góes, Universidade Federal do Rio de Janeiro, CCS, Bloco I, Room I-2-066, 22205-020, Rio de Janeiro, Brazil Queto, TúlioDepartment of Pediatrics, Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, FIOCRUZ, Avenue Rui Barbosa 716, 22250-020 Rio de Janeiro, RJ, Brazil Jones, CarlaDepartment of Immunology, Instituto de Microbiologia Professor Paulo de Góes, Universidade Federal do Rio de Janeiro, CCS, Bloco I, Room I-2-066, 22205-020, Rio de Janeiro, Brazil Arruda, Maria AugustaFarmanguinhos, FIOCRUZ, Avenue Comandante Guaranys No. 447, Jacarepaguá, 22775-903 Rio de Janeiro, RJ, Brazil Cunha, Thiago MattarDepartment of Pharmacology, Faculdade de Medicina da USP, Avenue Bandeirantes 3900, Monte Alegre, 14049-900 Ribeirão Preto, SP, Brazil Cunha, Fernando QueirozDepartment of Pharmacology, Faculdade de Medicina da USP, Avenue Bandeirantes 3900, Monte Alegre, 14049-900 Ribeirão Preto, SP, Brazil Gaspar-Elsas, Maria IgnezDepartment of Pediatrics, Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, FIOCRUZ, Avenue Rui Barbosa 716, 22250-020 Rio de Janeiro, RJ, Brazil The Scientific World Journal20132087052013 SCOAP3Hindawi https://doi.org/10.1155/2013/208705Full text URL
oai:hindawi.com:10.1155/2013/937935 2014-05-19T12:06:50Z HINDAWI.TSWJ:2013
10.1155/2013/937935DOI Radon, KatjaInstitute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Hospital of the Ludwig-Maximilians University (LMU), 80336 Munich, GermanyORCID-0000-0002-5271-3972 Childhood Asthma and Allergies in Urban, Semiurban, and Rural Residential Sectors in Chile Hindawi Publishing Corporation2013-05-23 4 While rural living protects from asthma and allergies in many countries, results are conflicting in Latin America. We studied the prevalence of asthma and asthma symptoms in children from urban, semiurban, and rural sectors in south Chile. A cross-sectional questionnaire study was conducted in semiurban and rural sectors in the province of Valdivia (n=559) using the ISAAC (International Study of Asthma and Allergies in Childhood) questionnaire. Results were compared to prevalence in urban Valdivia (n=3105) by using data from ISAAC III study. Odds ratios (+95% confidence intervals) were calculated. No statistical significant differences were found for asthma ever and eczema symptoms stratified by residential sector, but a gradient could be shown for current asthma and rhinoconjunctivitis symptoms with urban living having highest and rural living having lowest prevalence. Rural living was inversely associated in a statistical significant way with current asthma (OR: 0.4; 95% CI: 0.2–0.9) and rhinoconjunctivitis symptoms (OR: 0.3; 95% CI: 0.2–0.7) in logistic regression analyses. Rural living seems to protect from asthma and respiratory allergies also in Chile, a South American country facing epidemiological transition. These data would be improved by clinical studies of allergic symptoms observed in studied sectors. CC-BY-3.0http://creativecommons.org/licenses/by/3.0/ Copyright © 2013 Leonie Kausel et al. Kausel, LeonieBiochemistry Faculty, Universidad Austral de Chile, Valdivia, ChileORCID-0000-0001-8240-3302 Boneberger, AnjaInstitute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Hospital of the Ludwig-Maximilians University (LMU), 80336 Munich, Germany Calvo, MarioMedical Faculty, Universidad Austral de Chile, Valdivia, Chile The Scientific World Journal20139379352013 SCOAP3Hindawi https://doi.org/10.1155/2013/937935Full text URL
oai:hindawi.com:10.1100/2012/909524 2014-08-04T06:22:44Z HINDAWI.TSWJ:2012
10.1100/2012/909524DOI Dubakiene, RutaVilnius University Faculty of Medicine, University Street 3 01513, Vilnius, Lithuania Studies on Early Allergic Sensitization in the Lithuanian Birth Cohort The Scientific World Journal2012-04-19 6 Cohort studies are of great importance in defining the mechanism responsible for the development of allergy-associated diseases, such as atopic dermatitis, allergic asthma, and allergic rhinoconjunctivitis. Although these disorders share genetic and environmental risk factors, it is still under debate whether they are linked or develop sequentially along an atopic pathway. The current study was aimed to determine the pattern of allergy sensitization in the Lithuanian birth cohort “Alergemol” (n = 1558) established as a part of the multicenter European birth cohort “EuroPrevall”. Early sensitization to food allergens in the “Alergemol” birth cohort was analysed. The analysis revealed 1.3% and 2.8% of symptomatic-sensitized subjects at 6 and 12 months of age, respectively. The sensitization pattern in response to different allergens in the group of infants with food allergy symptoms was studied using allergological methods in vivo and in vitro. The impact of maternal and environmental risk factors on the early development of food allergy in at 6 and 12 months of age was evaluated. Our data showed that maternal diet, diseases, the use of antibiotics, and tobacco smoke during pregnancy had no significant impact on the early sensitization to food allergens. However, infants of atopic mothers were significantly more often sensitized to egg as compared to the infants of nonatopic mothers. CC-BY-3.0http://creativecommons.org/licenses/by/3.0/ Copyright © 2012 Ruta Dubakiene et al. Rudzeviciene, OdilijaVilnius University Faculty of Medicine, University Street 3 01513, Vilnius, Lithuania Butiene, IndreVilnius University Faculty of Medicine, University Street 3 01513, Vilnius, Lithuania Sezaite, IndreInstitute of Biotechnology of Vilnius University, Graiciuno Street 8 02241, Vilnius, Lithuania Petronyte, MalvinaVilnius University Faculty of Medicine, University Street 3 01513, Vilnius, Lithuania Vaicekauskaite, DaliaVilnius University Faculty of Medicine, University Street 3 01513, Vilnius, Lithuania Zvirbliene, AurelijaInstitute of Biotechnology of Vilnius University, Graiciuno Street 8 02241, Vilnius, Lithuania The Scientific World Journal20129095242012 SCOAP3Hindawi https://doi.org/10.1100/2012/909524Full text URL
oai:hindawi.com:10.1100/tsw.2004.191 2014-08-18T12:08:23Z HINDAWI.TSWJ:4
10.1100/tsw.2004.191DOI Clinical Holistic Medicine: Developing from Asthma, Allergy, and Eczema TheScientificWorldJOURNAL1900-01-01 7 This paper shows how consciousness-based holistic medicine can be used in the case of asthma, allergy, and eczema. We have many fine drugs to relieve patients from the worst of these symptoms, where many children and adults suffer health problems related to hyper-reactivity of the immune system. Many symptoms remain throughout life because the drugs do not cure the allergy and allergy today is the sixth leading cause of chronic illness. The etiology of the immune disturbances is mostly unknown from a biomedical perspective. Consciousness-based holistic medicine could therefore be used to treat these diseases if the patient is willing to confront hidden existential pain, is motivated to work hard, and is dedicated to improve quality of life, quality of working life, and personal relationships. Improving quality of life is not always an easy job for the patient, but it can be done with coaching from the physician. An increased physical health is often observed after only a few sessions with a physician skilled in using holistic medical tools and able to coach the patient successfully through a few weeks of dedicated homework. Children with allergy and asthma can also be helped if their parents are able to do work on personal development, to improve the general quality of life in the family and their relationship with the child. CC-BY-3.0http://creativecommons.org/licenses/by/3.0/ Copyright © 2004 Søren Ventegodt et al. Ventegodt, SørenThe Quality of Life Research Center, Teglgårdstræde 4-8, DK-1452 Copenhagen K, Denmark Morad, MohammedClalit Health Services and Division of Community Health, Ben Gurion University, Beer-Sheva, Israel Merrick, JoavNational Institute of Child Health and Human Development, Office of the Medical Director, Division for Mental Retardation, Ministry of Social Affairs, Jerusalem and Zusman Child Development Center, Division of Pediatrics and Community Health, Ben Gurion University, Beer-Sheva, Israel TheScientificWorldJOURNAL42004 SCOAP3Hindawi https://doi.org/10.1100/tsw.2004.191Full text URL
oai:hindawi.com:10.1100/tsw.2007.134 2014-11-20T09:43:35Z HINDAWI.TSWJ:7
10.1100/tsw.2007.134DOI Stankovic, IvanaThe Clinic for Lung Diseases and TBC, University Hospital, Niš, Serbia Is There Any Point in a Corticosteroid Treatment of Intermittent Asthma? TheScientificWorldJOURNAL1900-01-01 8 International guidelines advocate the early introduction of inhaled corticosteroids (ICS) in all types of persistent asthma. Our study was undertaken to assess the effects of ICS on bronchial hyperresponsiveness (BHR) as a hallmark of inflammation, and to assess the symptoms, the use of rescue medications, and the parameters of lung function in patients with mild intermittent asthma. The patients with intermittent asthma (n = 85) were randomly allocated to a treatment with ICS, beclomethasone dipropionate 250 μg/day and short-acting β2 agonists salbutamol as needed (Group A, n = 45) or to a treatment with only short-acting β2 agonists as needed (Group B, n = 40) during the 6-month treatment period. At the end of the study, in Group A, we found a statistically significant decrease of BHR (PD20 0.98 vs. 2.07) (p < 0.001), diurnal peak expiratory flow (PEF) variability (17.9 vs. 13.8) (p < 0.001), symptom scores (0.63 vs. 0.30) (p < 0.001), and used rescue medication (p < 0.001), while the parameters of lung function remained unchanged except for forced expiratory volume in 1 sec (FEV1), which had a statistically significant increase (3.58 vs. 3.66) (p < 0.001). In Group B, there was a statistically significant decrease of lung function parameters FEV1 (3.80 vs. 3.71) (p < 0.001), forced vital capacity (FVC) (4.43 vs. 4.37) (p < 0.001), FEV1/FVC (88.2 vs. 85.3) (p < 0.05), PEF (8.05 vs. 7.51) (p < 0.01), PEF variability (17.85 vs. 18.33) (p < 0.001), increased BHR (PD20 1.04 vs. 0.62) (p < 0.05), and symptom scores (0.46 vs. 0.62) (p < 0.01), as well as the use of rescue medication during the day (p < 0.001). Early introduction of low doses of ICS may be more beneficial than β2 agonists alone in patients with intermittent asthma. CC-BY-3.0http://creativecommons.org/licenses/by/3.0/ Copyright © 2007 Ivana Stankovic et al. Pejcic, TatjanaThe Clinic for Lung Diseases and TBC, University Hospital, Niš, Serbia Milenkovic, BranislavaThe Institute for Lung Diseases, University Hospital, Belgrade, Serbia Jovanovic, DraganaThe Institute for Lung Diseases, University Hospital, Belgrade, Serbia Rancic, MilanThe Clinic for Lung Diseases and TBC, University Hospital, Niš, Serbia TheScientificWorldJOURNAL72007 SCOAP3Hindawi https://doi.org/10.1100/tsw.2007.134Full text URL
oai:hindawi.com:10.1100/tsw.2002.810 2014-12-09T14:40:51Z HINDAWI.TSWJ:2
10.1100/tsw.2002.810DOI Haeggström, Jesper Z.Department of Medical Biochemistry and Biophysics, Division of Chemistry 2, Karolinska Institutet, S-171 77 Stockholm, Sweden Functional Properties and Molecular Architecture of Leukotriene A4 Hydrolase, a Pivotal Catalyst of Chemotactic Leukotriene Formation TheScientificWorldJOURNAL1900-01-01 16 The leukotrienes are a family of lipid mediators involved in inflammation and allergy. Leukotriene B4 is a classical chemoattractant, which triggers adherence and aggregation of leukocytes to the endothelium at only nM concentrations. In addition, leukotriene B4 modulates immune responses, participates in the host defense against infections, and is a key mediator of PAF-induced lethal shock. Because of these powerful biological effects, leukotriene B4 is implicated in a variety of acute and chronic inflammatory diseases, e.g., nephritis, arthritis, dermatitis, and chronic obstructive pulmonary disease. The final step in the biosynthesis of leukotriene B4 is catalyzed by leukotriene A4 hydrolase, a unique bifunctional zinc metalloenzyme with an anion-dependent aminopeptidase activity. Here we describe the most recent developments regarding our understanding of the function and molecular architecture of leukotriene A4 hydrolase. CC-BY-3.0http://creativecommons.org/licenses/by/3.0/ Copyright © 2002 Jesper Z. Haeggstrom et al. Nordlund, Pär2Department of Biochemistry, University of Stockholm, Arrhenius Laboratories A4, S-106 91 Stockholm, Sweden Thunnissen, Marjolein M.G.M.2Department of Biochemistry, University of Stockholm, Arrhenius Laboratories A4, S-106 91 Stockholm, Sweden TheScientificWorldJOURNAL22002 SCOAP3Hindawi https://doi.org/10.1100/tsw.2002.810Full text URL
oai:hindawi.com:10.1100/tsw.2007.139 2015-03-01T06:45:28Z HINDAWI.TSWJ:7
10.1100/tsw.2007.139DOI Masini, EmanuelaDepartment of Preclinical and Clinical Pharmacology, University of Florence, Italy Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders TheScientificWorldJOURNAL1900-01-01 80 Amine oxidases (AOs) are ubiquitous enzymes involved in the metabolism of biogenic amines. Copper AOs (Cu-AOs) catalyze the oxidative deamination of primary amine groups of several biogenic amines, such as putrescine, cadaverine, and histamine. In the present review, the effects of a plant amine oxidase (Cu-AO, histaminase, EC1.4.3.6) purified from pea seedlings in the modulation of IgE-mediated allergic reactions, and in the prevention of cardiac and splachnic postischemic reperfusion damage are reported. CC-BY-3.0http://creativecommons.org/licenses/by/3.0/ Copyright © 2007 Emanuela Masini et al. Bani, DanielleDepartment of Anatomy, Histology and Forensic Medicine, Section of Histology, University of Florence, Italy Marzocca, CosimoDepartment of Preclinical and Clinical Pharmacology, University of Florence, Italy Mateescu, Mircea AlexandruDepartment of Chemistry and Biochemistry, Université du Québec à Montréal, Montreal (Quebec), Canada Mannaioni, Pier FrancescoDepartment of Preclinical and Clinical Pharmacology, University of Florence, Italy Federico, RodolfoDepartment of Biology, University of Rome, Italy Mondovì, BrunoDepartment of Biochemical Sciences “A. Rossi Fanelli”, Rome University “La Sapienza”, Rome, Italy TheScientificWorldJOURNAL72007 SCOAP3Hindawi https://doi.org/10.1100/tsw.2007.139Full text URL
oai:hindawi.com:10.1100/2012/474020 2015-11-09T07:37:38Z HINDAWI.TSWJ:2012
10.1100/2012/474020DOI Negrete-Garcia, Ma. CristinaDepartment of Immunogenetics and Allergy, Instituto Nacional de Enfermedades Respiratorias, Calzada Tlalpan 4502, 14080 Mexico, DF, Mexico Galectin-10 Is Released in the Nasal Lavage Fluid of Patients with Aspirin-Sensitive Respiratory Disease The Scientific World Journal2012-04-30 6 The aim of this work was to determine the presence of galectin-10 in nasal lavage fluid (NLF) of patients with aspirin-sensitive respiratory disease (ASRD) before and after challenge with L-ASA (aspirin) by ELISA. Fifteen ASRD patients, ten aspirin-tolerant asthmatics (ATA), and fifteen healthy controls (HC) were studied. The baseline presence of Galectin-10 in PBMC was determined using real time PCR. Galectin-10 was evaluated in tissue of nasal polyps by western blot. Our results showed a lower expression in PBMC of ASRD patients than in ATA and healthy controls. However, a higher concentration of galectin-10 in NLF was found in ASRD patients before and after L-ASA challenge; western blot confirmed a high expression of galectin-10 in tissue from nasal polyps obtained from ASRD patients. Our results suggest a probable role of galectin-10 in the inflammatory response observed in ASRD patients; however, confirmatory studies are needed. CC-BY-3.0http://creativecommons.org/licenses/by/3.0/ Copyright © 2012 Ma. Cristina Negrete-Garcia et al. Jiménez-Torres, Carla YoneliDepartment of Immunogenetics and Allergy, Instituto Nacional de Enfermedades Respiratorias, Calzada Tlalpan 4502, 14080 Mexico, DF, Mexico Alvarado-Vásquez, NoeDepartment of Biochemistry, Instituto Nacional de Enfermedades Respiratorias, Calzada Tlalpan 4502, 14080 Mexico, DF, Mexico Montes-Vizuet, A. RosalíaDepartment of Immunogenetics and Allergy, Instituto Nacional de Enfermedades Respiratorias, Calzada Tlalpan 4502, 14080 Mexico, DF, Mexico Velázquez-Rodriguez, J. R.Department of Immunogenetics and Allergy, Instituto Nacional de Enfermedades Respiratorias, Calzada Tlalpan 4502, 14080 Mexico, DF, Mexico Jimenez-Martinez, M. CarmenDepartment of Immunology, Research Unit, Institute of Ophthalmology, Foundation Conde de Valenciana, 06800 Mexico, DF, Mexico Teran-Juárez, Luis ManuelDepartment of Immunogenetics and Allergy, Instituto Nacional de Enfermedades Respiratorias, Calzada Tlalpan 4502, 14080 Mexico, DF, Mexico The Scientific World Journal20124740202012 SCOAP3Hindawi https://doi.org/10.1100/2012/474020Full text URL
oai:hindawi.com:10.1155/2015/940243 2015-12-24T07:54:08Z HINDAWI.TSWJ:2015
10.1155/2015/940243DOI Sénéchal, HélèneAllergy & Environment Team, Biochemistry Department, Armand Trousseau Children Hospital (AP-HP), 26 avenue du Dr. Arnold Netter, 75571 Paris, France Sutra, Jean-PierreAllergy & Environment Team, Biochemistry Department, Armand Trousseau Children Hospital (AP-HP), 26 avenue du Dr. Arnold Netter, 75571 Paris, France A Review of the Effects of Major Atmospheric Pollutants on Pollen Grains, Pollen Content, and Allergenicity Hindawi Publishing Corporation2015-12-24 29 This review summarizes the available data related to the effects of air pollution on pollen grains from different plant species. Several studies carried out either on in situ harvested pollen or on pollen exposed in different places more or less polluted are presented and discussed. The different experimental procedures used to monitor the impact of pollution on pollen grains and on various produced external or internal subparticles are listed. Physicochemical and biological effects of artificial pollution (gaseous and particulate) on pollen from different plants, in different laboratory conditions, are considered. The effects of polluted pollen grains, subparticles, and derived aeroallergens in animal models, in in vitro cell culture, on healthy human and allergic patients are described. Combined effects of atmospheric pollutants and pollen grains-derived biological material on allergic population are specifically discussed. Within the notion of “polluen,” some methodological biases are underlined and research tracks in this field are proposed. CC-BY-3.0http://creativecommons.org/licenses/by/3.0/ Copyright © 2015 Hélène Sénéchal et al. Visez, NicolasPhysical Chemistry of Combustion and Atmosphere Processes (PC2A), UMR CNRS 8522, University of Lille, 59655 Villeneuve d’Ascq, France Charpin, DenisPneumo-Allergology Department, North Hospital, 265 chemin des Bourrely, 13915 Marseille 20, France Shahali, YoucefAllergy & Environment Team, Biochemistry Department, Armand Trousseau Children Hospital (AP-HP), 26 avenue du Dr. Arnold Netter, 75571 Paris, FrancePersiflore, 18 avenue du Parc, 91220 Le Plessis-Pâté, France Peltre, GabrielCNRS, 75794 Paris 16, France Biolley, Jean-PhilippeSEVE Team, Ecology and Biology of Interactions (EBI), UMR-CNRS-UP 7267, University of Poitiers, 3 rue Jacques Fort, 86073 Poitiers, France Lhuissier, FranckKeyGene, P.O. Box 216, 6708 AE Wageningen, Netherlands Couderc, RémyBiochemistry Department, Armand Trousseau Children Hospital (AP-HP), 26 avenue du Dr. Arnold Netter, 75571 Paris 12, France Yamada, OhriFrench Agency for Food, Environmental and Occupational Health Safety, 14 rue Pierre et Marie Curie, 94701 Maisons-Alfort, France Malrat-Domenge, AudreyFrench Agency for Food, Environmental and Occupational Health Safety, 14 rue Pierre et Marie Curie, 94701 Maisons-Alfort, France Pham-Thi, NhânAllergology Department, Pasteur Institute, 25-28 rue du Dr. Roux, 75724 Paris 15, France Poncet, PascalAllergy & Environment Team, Biochemistry Department, Armand Trousseau Children Hospital (AP-HP), 26 avenue du Dr. Arnold Netter, 75571 Paris, FranceInfections & Epidemiology Department, Pasteur Institute, 25-28 rue du Dr. Roux, 75724 Paris 15, France The Scientific World Journal20159402432015 SCOAP3Hindawi https://doi.org/10.1155/2015/940243Full text URL